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NIAGEN BIOSCIENCE INC (NAGE)

Sector: Consumer Staples

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2026 Annual Meeting Analysis

NIAGEN BIOSCIENCE INC · Meeting: June 24, 2026

Policy v1.2high confidenceView Filing ↗
For informational purposes only. This AI-generated analysis applies a published voting policy to publicly available proxy filings. It does not constitute investment advice, proxy voting advice, or a solicitation of any kind. AI analysis may be incomplete or inaccurate — always review the actual filing and make your own independent decision.

Directors FOR

7

Directors AGAINST

1

Say on Pay

AGAINST

Auditor

FOR

Director Elections

Election of Eight Director Nominees

7 FOR/1 AGAINST

Against Analysis

✗ AGAINST
Steven Rubin⚑ overboarding: serves on 5+ public company boards (NAGE, OPK, COCP, ENTX, RDVT, previously others)

Mr. Rubin currently holds public board seats at Niagen Bioscience, OPKO Health, Cocrystal Pharma, Entera Bio, and Red Violet — that is at least five public company board seats simultaneously, which exceeds the policy limit of four; this level of board commitments raises concern that he cannot devote adequate time and attention to each board.

For Analysis

✓ FOR
Frank Jaksch, Jr.

Long-tenured co-founder and Chairman with deep industry knowledge; the company's 3-year price return of +255.2% outperforms XBI (SPDR S&P Biotech ETF) by +197.3 percentage points, well above the 65pp threshold required to trigger a vote against, so no TSR concern applies; no overboarding, attendance, or independence issues identified.

✓ FOR
Robert Fried

CEO and executive director with relevant experience; the company's 3-year price return of +255.2% outperforms XBI (SPDR S&P Biotech ETF) by +197.3 percentage points, well above the 65pp threshold required to trigger a vote against; no attendance or overboarding concerns identified.

✓ FOR
Wendy Yu

Director with relevant marketing and management experience representing a major investor; the company's strong 3-year TSR outperforms XBI (SPDR S&P Biotech ETF) by +197.3 percentage points, well above the 65pp trigger threshold; no overboarding, attendance, or independence issues identified.

✓ FOR
Gary Ng

Director with retail industry expertise representing a major investor; the company's 3-year price return of +255.2% outperforms XBI (SPDR S&P Biotech ETF) by +197.3 percentage points, well above the 65pp threshold; the proxy confirms attendance above 75% and no overboarding concerns are apparent.

✓ FOR
Kristin Patrick

Independent director with extensive consumer marketing experience; the company's 3-year TSR outperforms XBI (SPDR S&P Biotech ETF) by +197.3 percentage points, well above the 65pp trigger threshold; no attendance, overboarding, or independence concerns identified.

✓ FOR
Ann Cohen

Independent director and Audit Committee Chair with strong financial credentials including CPA designation and senior CFO experience, satisfying the financial expertise requirement for audit committee service; the company's 3-year TSR outperforms XBI (SPDR S&P Biotech ETF) by +197.3 percentage points, well above the 65pp trigger threshold.

✓ FOR
Hamed Shahbazi

Independent director with relevant technology and operational expertise as a founder and CEO of WELL Health Technologies; the company's 3-year TSR outperforms XBI (SPDR S&P Biotech ETF) by +197.3 percentage points, well above the 65pp trigger threshold; one late Form 4 filing is noted but is an administrative issue, not a governance trigger under policy.

Seven of eight directors receive a FOR vote; Steven Rubin is flagged AGAINST solely due to overboarding — he simultaneously holds board seats at five public companies, exceeding the policy limit of four. The company's exceptional 3-year total shareholder return of +255.2%, which outperforms the XBI (SPDR S&P Biotech ETF) benchmark by +197.3 percentage points, means the TSR trigger does not apply to any director. All directors met the 75% attendance requirement. Ann Cohen, who serves as Audit Committee Chair, has appropriate financial qualifications as a CPA and former CFO.

Say on Pay

✗ AGAINST

CEO

Robert Fried

Total Comp

$8,381,900

Prior Support

97%%

⚑ CEO total compensation of $8,381,900 is materially above benchmark for a biotech CEO at a ~$381M market cap company — dominated by a one-time award of 1,518,600 performance stock units with a reported value of $5,220,188⚑ PSU award structure: while stock-price-hurdle-based performance conditions exist ($15–$50 VWAP thresholds), the award was sized so large relative to the company's current stock price and market cap that it represents an outsized single grant; current stock price of $4.76 means the first hurdle ($15 VWAP) requires more than a 3x increase⚑ Pay-for-performance concern: 1-year stock return of -38.8% versus XBI (SPDR S&P Biotech ETF) 1-year return of +58.0%, a gap of -96.8 percentage points, in the same year the CEO received an $8.4M pay package⚑ CEO fixed salary of $650,000 represents only ~7.8% of total reported compensation — pay mix is heavily variable, which is structurally positive, but the sheer scale of the one-time PSU grant inflates total compensation dramatically above benchmark

CEO Robert Fried's total reported compensation of $8,381,900 for 2025 is driven primarily by a single one-time award of 1,518,600 performance stock units with a reported grant-date value of $5,220,188 — that is one large award covering a seven-year performance period but reported entirely in the current year, making it appear far above what a biotech CEO at a roughly $381 million company would typically earn. While the performance stock units do require the stock price to reach $15 to $50 thresholds (more than triple to more than ten times the current stock price) and could ultimately deliver nothing if those targets are missed, the reported value still triggers a significant above-benchmark flag under our pay level test. Compounding the concern is that in the same year this compensation was granted, the company's stock fell nearly 39% while the XBI (SPDR S&P Biotech ETF) rose 58%, a gap of nearly 97 percentage points — meaning shareholders experienced steep losses while the CEO received a historically large pay package, which fails the pay-for-performance alignment check for incentive compensation granted above benchmark during a period of severe underperformance relative to biotech peers.

Auditor Ratification

✓ FOR

Auditor

Crowe LLP

Tenure

1 yrs

Audit Fees

$483,000

Non-Audit Fees

$0

Crowe LLP has served as the company's auditor only since December 2024 — roughly one year — so there is no long-tenure independence concern; the company paid zero non-audit fees in 2025, meaning the non-audit fee ratio is 0%, well below the 50% threshold that would raise independence concerns; Crowe is a large national accounting firm appropriate for a company of this size.

Overall Assessment

The 2026 Niagen Bioscience annual meeting presents three proposals: director elections, auditor ratification, and a Say on Pay vote. We vote FOR six of eight directors (AGAINST Steven Rubin due to overboarding), FOR auditor Crowe LLP (short tenure, zero non-audit fees), and AGAINST the Say on Pay proposal due to an outsized CEO pay package of $8.4 million — anchored by a large one-time performance stock unit grant — that was awarded in a year when the company's stock fell nearly 39% while the XBI (SPDR S&P Biotech ETF) benchmark rose 58%.

Filing date: April 29, 2026·Policy v1.2·high confidence