Alessandra Cesano, age 65, has served as a member of our Board of Directors since November 2022. Dr. Cesano has 28 years of experience in research and development in both drug and diagnostic companies ranging from large, global biopharma to private, venture-backed companies. Dr. Cesano served as Chief Medical Officer of ESSA Pharma from July of 2019 through May of 2025. Prior to her time at ESSA Pharma, Dr. Cesano was the Chief Medical Officer at NanoString Inc., where she built and led the Immuno-Oncology program and the diagnostic pipeline. Prior to NanoString, she was Chief Medical Officer for Cleave Biosciences. At Cleave Biosciences, Dr. Cesano led the successful filing of two Investigational New Drug (IND) Applications for a clinical candidate and led two Phase I trials in Multiple Myeloma and solid tumors. Dr. Cesano has global full-phase development and regulatory experience with large and small molecules and had a substantive and lead role in two approved drugs Kepivance (palifermin) and Vectibix (panitumumab). Dr. Cesano currently serves on the board of directors at Puma Biotechnology, Inc., a public company, Zymeworks Inc., a public company, and Tolremo, a private company. She received her PhD in tumor immunology and her MD from the University of Turin. The Board of Directors has determined that Dr. Cesano qualifies as an independent director under applicable Nasdaq listing rules. We believe Dr. Cesano is qualified to serve on our Board of Directors because of her expertise in the biopharmaceutical industry focused on oncology.